Without a doubt, my favortie moment in video games. Just mention "star wolf" to anyone who owned the game and they will instantly remember each line ("Why are ships coming out of the base?"..."What the heck?"). Seriously, it is such a thrill the first time star wolf comes shooting at you from the sky while you simotaneously hear the memorable quotes and the best video game music ever. In fact, almost the entire game is like that (great music/quotes and fun as hell).
"CAN'T LET YOU DO THAT, STAR FOX!" - "Andross has ordered us to take you down." - "Hey Peppy! Long time no see!" - "Andross' enemy is my enemy."